Posttraumatic strain disorder (PTSD) had a prevalence of 30.2% amongst acute COVID-19 infection survivors, researchers identified in a cross-sectional study published in JAMA Psychiatry. They identified that females, these with history of psychiatric problems, and these who experienced acute COVID-19 qualities of delirium or agitation and persistent COVID-19 symptoms had been more probably to create PTSD.
The researchers sought to discover out no matter if the prevalence of PTSD in COVID-19 survivors was comparable to that identified in preceding coronavirus epidemics, which according to meta-analytics findings was 32.2% (95% CI, 23.7-42.).
The researchers studied information of 381 consecutive White patients (166 females, 215 males) who had presented to the emergency division with SARS-CoV-2 and recovered from the COVID-19 infection inside 30 to 120 days. The patients then had been referred for postrecovery overall health verify to a post-acute care service April 21, 2020, to October 15, 2020, in Rome, Italy.
The patients had a imply age of 55.26 years (typical deviation [SD]: 14.86 variety, 18-89). The vast majority (309 of 381) had been hospitalized through the acute COVID-19 illness, with a imply keep of 18.41 (17.27) days.
Psychiatrists diagnosed PTSD according to the criterion-typical Clinician-Administered PTSD Scale for DSM-5 (CAPS-5). They reached a Cohen κ interrater reliability of .82. The patients had to have had at least 1 DSM-5 criterion B and C symptom, at least 2 criterion D and E symptoms, and each Criteria F and G.
PTSD was identified in 115 participants (30.2%). Other diagnoses incorporated depressive episode (66 [17.3%]), hypomanic episode (3), generalized anxiousness disorder (27 [7.0%]), and psychotic problems (1).
Data from all patients, with and with out PTSD, had been compared with the χ2 test for nominal variables and a single-way evaluation of variance for continuous variables.
The researchers identified that patients with PTSD had been more probably to be females (64 [55.7%]), reported larger prices of history of psychiatric problems (40 [34.8%]) and delirium or agitation through acute illness (19 [16.5%]), and presented with more persistent healthcare symptoms in the post-illness stage (more than 3 symptoms, 72 [62.6%]).
Logistic regression especially identified sex (Wald1 = 4.79 P =.02), delirium or agitation (Wald1 = 5.14 P =.02), and persistent healthcare symptoms (Wald2 = 12.46 P =.002) as aspects connected with PTSD.
The limitations of the study incorporated its modest sample size and cross-sectional style due to the fact PTSD symptom prices can differ more than time. The single-center study also did not involve a manage group of patients who presented to the emergency division for other factors.
Disclosure: One study author declared affiliations with the market. Please see the original reference for a complete list of authors’ disclosures.
Janiri D, Carfi A, Kotzalidis GD, Bernabei R, Landi F, Sani G. Gemelli Against COVID-19 Post-Acute Care Study Group. Posttraumatic stress disorder in patients after severe COVID-19 infection. JAMA Psychiatry. Published on the net February 18, 2021. doi:10.1001/jamapsychiatry.2021.0109