Severe COVID-19 Infection Associated With Worse Mental Health Symptoms

Severe COVID-19 Infection Associated With Worse Mental Health Symptoms

Chronic COVID-19 symptoms, also named “long COVID,” present not only ongoing physical challenges, but also a larger danger for depression and anxiousness. The locating comes from an observational study on nonhospitalized patients with COVID-19 who experienced symptoms up to 16 months right after diagnosis. Researchers published their huge observational study in Lancet Public Health.

While public wellness officials have discovered significantly about the lingering physical symptoms of lengthy COVID, they know much less about the ongoing mental wellness effect. To assist the health-related neighborhood greater comprehend the association involving lengthy COVID and mental wellness, researchers carried out an observational study that integrated 7 cohorts from 6 nations: Denmark, Estonia, Iceland, Norway, Sweden, and the United Kingdom.

They evaluated the date of diagnosis, days bedridden due to COVID-19, and symptoms reports up to 16 months from diagnosis. They also utilized numerous mental wellness assessments to assess depression and anxiousness. The analytical cohort integrated 247,249 people. Of these, 4% tested positive for COVID-19 throughout the study period.

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The researchers discovered that the longer patients had been bedridden, the larger the odds of symptoms of depression and anxiousness. The final results show a clear hyperlink involving COVID-19 distress and time from diagnosis. The prevalence ratio (PR) for depressive symptoms was 1.30 (95% CI 1.07–1.59) and COVID-19-connected distress was 1.20 (1.09–1.33) inside 2 months right after diagnosis but was not statistically considerable beyond 2 months right after diagnosis.

Compared with COVID-19-damaging patients, patients bedridden for 7 days or longer showed persistent symptoms of depression (PR 1.66 [95% CI 1.11–2.47] at to 2 months right after diagnosis 1.53 [1.26–1.86] at more than 2 months to 6 months right after diagnosis and 1.60 [1.17–2.81] at more than 6 months to 16 months right after diagnosis). Anxiety symptoms had been present at a comparable price: (PR 1.47 [95% CI 0.80–2.72] at to 2 months right after diagnosis 1.46 [1.20–1.79] at more than 2 to 6 months right after diagnosis and 1.47 [1.19–1.81] at more than 6 months to 16 months right after diagnosis.

The study had a handful of limitations. COVID-19 diagnosis and mental wellness symptoms had been self-reported. In addition, most participants reported symptoms involving March and June 2020 when a lot of worry and uncertainty existed about COVID-19. However, it was a huge study that integrated more than 10,000 COVID-19-positive people from 6 European nations.

The final results of the study strengthen the understanding of the effect of lengthy COVID on mental wellness. “These findings motivate continued clinical vigilance and follow-up studies beyond the first year among individuals with the most severe symptomology after COVID-19 infections,” the researchers conclude.

Disclosure: Some study authors declared affiliations with biotech, pharmaceutical, and/or device businesses. Please see the original reference for a complete list of authors’ disclosures


Magnúsdóttir I, Lovik A, Unnarsdóttir AB, et al. Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational studyLancet Public Health. 2022S2468-2667(22)00042-1. doi:10.1016/S2468-2667(22)00042-1

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