A computerized adaptive diagnostic (CAD) screener that employed 5 or 6 things proficiently and quickly assessed post-traumatic tension disorder (PTSD) amongst veterans. These findings had been published in JAMA Network Open.
The CAD and computerized adaptive test (CAT) screeners for PTSD had been created employing a bank of 211 PTSD-linked things. The tools had been optimized employing a bifactorial model and simulating responses. The tools had been optimized by recruiting veterans (n=713) at a mountain state metropolitan Veterans Affairs Medical Center from 2017 to 2019 and validated with a subsample (n=304) of men and women.
The complete and subsample had a imply age of 52.8±15. and 47.1±12.6 years, 82.3% and 80.9% had been guys, 78.6% and 72.7% had been White, the imply duration of active-duty service was 8.2±7.5 and 7.2±6.4 years, and the imply quantity of deployments to combat zones had been 1.0±1.5 and 5.5±1.8, respectively.
Compared with responses to 203 things about PTSD, a subset of 10 things was strongly correlated (r, .95). This 10-item CAT-PTSD assessment took a median time of 59 (interquartile variety [IQR], 32-117) seconds to comprehensive.
A sensitivity evaluation was used to decide PTSD severity cutoffs. No PTSD vs mild PTSD corresponded with a CAT-PTSD score of 35 (sensitivity, 95% specificity, 51%), 47 for mild vs moderate (sensitivity, 79% specificity, 78%), and 60 for moderate vs extreme (sensitivity, 50% specificity, 93%).
With the subsample, the CAT-PTSD tool had an location beneath the curve (AUC) of .85 (95% CI, .79-.89), which did not differ from the complete 203-item PTSD questionnaire (AUC, .84 95% CI, .79-.89) and outperformed the PTSD Checklist for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (AUC, .75 95% CI, .68-.82).
For the CAD-PTSD tool, a 6-item interview of an person with no PTSD proficiently assessed the person as possessing a probability of PTSD of .01 and a 5-item interview of an person with PTSD with a probability of .81.
The CAD-PTSD tool was discovered to be correct (AUC, .91 95% CI, .87-.95), taking only 35 (IQR, 19-70) seconds to comprehensive.
These tools may possibly be restricted by not enabling for the monitoring or evaluation of PTSD-precise symptoms.
The study authors concluded that the CAD-PTSD and CAT-PTSD tools may possibly enable for speedy PTSD screening amongst veterans, potentially decreasing the burden for each patient and clinician in the routine veteran well being care setting.
Disclosure: Some study authors declared affiliations with biotech, pharmaceutical, device, and/or test businesses. Please see the original reference for a complete list of authors’ disclosures.
Brenner LA, Betthauser LM, Penzenik M, et al. Development and validation of computerized adaptive assessment tools for the measurement of posttraumatic stress disorder among US military veterans. JAMA Netw Open. 20214(7):e2115707. doi:10.1001/jamanetworkopen.2021.15707